President Biden’s incendiary “garbage” comment about Donald Trump supporters could have a big impact at the polls on Election Day, Bill Maher warned Friday — adding that it’s an even bigger blunder than Hilary Clinton calling them “a basket of deplorables” during the 2016 presidential campaign.

“I think it’s a bigger gaffe than people think,” the “Real Time” host said during his panel discussion. “It’s so funny, Joe Biden, his whole career, he was like Mr. Gaffe, and then here at the very end — he’s like Aaron Judge [in Game 5 of the World Series]. He just f–kin’ muffed the fly ball and at the end of the thing, and blew the whole [game].”

“Because I feel like it epitomizes everything that the Trump people hate about the Democrats. They look down at us. It’s like ‘deplorables’ times 10,” Maher added.

Clinton infamously told her 2016 backers to “stage an intervention” with friends who were planning on voting for her rival Trump.

“You know, to just be grossly generalistic, you could put half of Trump’s supporters into what I call the ‘basket of deplorables,’” she said at a campaign event.

The White House is under fire for allegedly altering official transcripts by adding an apostrophe to soften inflammatory remarks Biden made calling Trump’s supporters “garbage.”

Biden was responding to comedian Tony Hinchcliffe joking that Puerto Rico is a “floating island of garbage” during Trump’s Oct. 26 rally at Madison Square Garden.

“Did the Democrats look weak because they can’t take a joke?” Maher asked. “Because I think that’s another Achilles heel that they have.”

“Look, I have to defend my profession,” Maher later said. “I’m a comic. I’m a free speech absolutist. . . . This was offensive. But this guy’s an insult comic. Why is he at this [event] — it’s like bringing cocaine to a funeral.”